SR9009 kwayoyi 100 allunan/kwalba

Sunan samfur:Saukewa: SR9009

Fadada: 10 MG / kwaya 100 kwayoyi / kwalba

Farashin: $80/kwalba

MOQ: 1 kwalban

Lab: LianFu Bio

Bayanin samfur

SR9009, REV-ERBagonist, yana ƙara yawan danniya na kwayoyin halitta da aka tsara ta REV-ERBα/ERBβ (IC50: 670/800 nM).Ta hanyar kunna REV-ERB, SR9009 na iya rage ayyukan locomotor na circadian yayin lokacin duhu kuma ya canza yanayin yanayin yanayin agogo a cikin hypothalami na mice.Hakanan an canza tsarin circadian na furci na tsararrun kwayoyin halitta na rayuwa a cikin hanta, tsokar kwarangwal, da nama mai adipose a cikin berayen da aka fallasa ga SR9009, wanda ya haifar da ƙarin kashe kuzari.

SR9009 (100 mg/kg, ip, bid, na kwanaki 30) zai iyarage yawan kitseda alamainganta dyslipidemiakumahyperglycemia.